Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetSerine protease 1(Homo sapiens (Human))
University Of North Carolina

Curated by ChEMBL

LigandBDBM50368092(GNF-PF-3839 | PROPAMIDINE CHLORIDE)Copy SMILESCopy InChI

Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of trypsin by amidase assay.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
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TargetAcrosin(Sus scrofa)
TBA

Curated by ChEMBL

LigandBDBM50368092(GNF-PF-3839 | PROPAMIDINE CHLORIDE)Copy SMILESCopy InChI

Affinity DataKi:  3.50E+3nMAssay Description:Reversible competitive inhibition of boar spermatozoa acrosin using BzArgOEt as substrate by Dixon plot analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetTransmembrane protease serine 2(Homo sapiens (Human))TBA

LigandBDBM50368092(GNF-PF-3839 | PROPAMIDINE CHLORIDE)Copy SMILESCopy InChI

Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of TMPRSS2 (247 to 492 residues) (unknown origin) peptidase domain expressed in Escherichia coli BL21 (DE3) incubated for 30 mins followed...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBSimilars

In DepthDetails PubMed
Copy BDB DOI