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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50061849((S)-2-Benzenesulfonylamino-3-{3-[(5-carbamimidoyl-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory activity of fibrinogen binding to purified immobilized glycoprotein (fibrinogen receptor).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50061849((S)-2-Benzenesulfonylamino-3-{3-[(5-carbamimidoyl-...)
Affinity DataIC50:  35nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50061849((S)-2-Benzenesulfonylamino-3-{3-[(5-carbamimidoyl-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of 20 uM ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50061849((S)-2-Benzenesulfonylamino-3-{3-[(5-carbamimidoyl-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of vitronectin binding to the purified immobilized vitronectin receptor (alpha v, beta 3).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed