Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Nociceptin receptor
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50259236
(8-(bis(2-chlorophenyl)methyl)-3-phenyl-8-azabicycl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.70nM
Assay Description:
Displacement of [125I][Tyr14]nociceptin from human cloned NOP receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50259236
(8-(bis(2-chlorophenyl)methyl)-3-phenyl-8-azabicycl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 38nM
Assay Description:
Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50259236
(8-(bis(2-chlorophenyl)methyl)-3-phenyl-8-azabicycl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 268nM
Assay Description:
Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50259236
(8-(bis(2-chlorophenyl)methyl)-3-phenyl-8-azabicycl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.33E+3nM
Assay Description:
Displacement of [3H]diprenorphine from human delta opioid receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50259236
(8-(bis(2-chlorophenyl)methyl)-3-phenyl-8-azabicycl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.00E+3nM
Assay Description:
Inhibition of CYP2C9 (unknown origin) co-incubated with substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50259236
(8-(bis(2-chlorophenyl)methyl)-3-phenyl-8-azabicycl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.90E+4nM
Assay Description:
Inhibition of CYP2C9 (unknown origin) pre-incubated before addition of substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50259236
(8-(bis(2-chlorophenyl)methyl)-3-phenyl-8-azabicycl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP2D6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50259236
(8-(bis(2-chlorophenyl)methyl)-3-phenyl-8-azabicycl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP3A4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50259236
(8-(bis(2-chlorophenyl)methyl)-3-phenyl-8-azabicycl...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 376nM
Assay Description:
Agonist activity at human mu opioid assessed as stimulation of GDP-induced [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nociceptin receptor
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50259236
(8-(bis(2-chlorophenyl)methyl)-3-phenyl-8-azabicycl...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6nM
Assay Description:
Agonist activity at human NOP assessed as stimulation of GDP-induced [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI