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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50042493
(CGS-23885 | CHEMBL116719 | N-hydroxy-N-[(6-phenoxy...)
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Affinity Data
IC50: 37nM
Assay Description:
In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on 5-hydroxyeicosapentaenoic acid (5-HETE) production
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50042493
(CGS-23885 | CHEMBL116719 | N-hydroxy-N-[(6-phenoxy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on LTB4 production
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50042493
(CGS-23885 | CHEMBL116719 | N-hydroxy-N-[(6-phenoxy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 43nM
Assay Description:
In vitro inhibitory activity against 5-lipoxygenase by reduction of 5-hydroxyeicosatetraenoic acid (5-HETE) formed in guinea pig polymorphonuclear le...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50042493
(CGS-23885 | CHEMBL116719 | N-hydroxy-N-[(6-phenoxy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 48nM
Assay Description:
In vitro inhibitory activity against 5-lipoxygenase by reduction of LTB4 formed in guinea pig polymorphonuclear leukocytes (PMNs).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50042493
(CGS-23885 | CHEMBL116719 | N-hydroxy-N-[(6-phenoxy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 110nM
Assay Description:
In vitro inhibitory activity against 5-lipoxygenase by reduction of 5-hydroxyeicosatetraenoic acid (5-HETE) formed in guinea pig polymorphonuclear le...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid lipoxygenase ALOX12
(Homo sapiens (Human))
Ciba-Geigy
Curated by
ChEMBL
Ligand
BDBM50042493
(CGS-23885 | CHEMBL116719 | N-hydroxy-N-[(6-phenoxy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 640nM
Assay Description:
Inhibitory concentration against human platelet 12-lipoxygenase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50042493
(CGS-23885 | CHEMBL116719 | N-hydroxy-N-[(6-phenoxy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 890nM
Assay Description:
In vitro inhibitory activity against 5-lipoxygenase by reduction of LTB4 formed in guinea pig polymorphonuclear leukocytes (PMNs).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thromboxane-A synthase
(Rattus norvegicus)
Ciba-Geigy
Curated by
ChEMBL
Ligand
BDBM50042493
(CGS-23885 | CHEMBL116719 | N-hydroxy-N-[(6-phenoxy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibitory concentration against human platelet thromboxane synthetase
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin G/H synthase 1/2
(Homo sapiens (Human))
Ciba-Geigy
Curated by
ChEMBL
Ligand
BDBM50042493
(CGS-23885 | CHEMBL116719 | N-hydroxy-N-[(6-phenoxy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.60E+4nM
Assay Description:
In vitro inhibitory activity against 5-lipoxygenase by reduction of 5-hydroxyeicosatetraenoic acid (5-HETE) formed in guinea pig polymorphonuclear le...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI