Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International

US Patent

LigandBDBM191395(US9181272, 165 | US9181272, 262 | US9181272, 263)Copy SMILESCopy InChI

Affinity DataIC50:  12.4nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...More data for this Ligand-Target Pair

Target InfoMMDB
UniProtKB/TrEMBL
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International

US Patent

LigandBDBM191395(US9181272, 165 | US9181272, 262 | US9181272, 263)Copy SMILESCopy InChI

Affinity DataIC50:  47nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...More data for this Ligand-Target Pair

Target InfoMMDB
UniProtKB/TrEMBL
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International

US Patent

LigandBDBM191395(US9181272, 165 | US9181272, 262 | US9181272, 263)Copy SMILESCopy InChI

Affinity DataIC50:  159nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...More data for this Ligand-Target Pair

Target InfoMMDB
UniProtKB/TrEMBL
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI