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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Mineralocorticoid receptor
(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Ligand
BDBM121427
(US8722709, 31)
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Affinity Data
IC50: 13nM
pH: 7.4
Assay Description:
The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Mineralocorticoid receptor
(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Ligand
BDBM121427
(US8722709, 31)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Displacement of TAMRA-labeled dexamethasone from full-length human mineralocorticoid receptor expressed in baculovirus infected insect cells after 60...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mineralocorticoid receptor
(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Ligand
BDBM121427
(US8722709, 31)
Copy SMILES
Copy InChI
Affinity Data
IC50: 44nM
Assay Description:
Antagonist activity at Gal4-fused human MR LBD expressed in HEK293T cells assessed as inhibition of aldosterone-induced transactivation activity afte...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI