Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM121427(US8722709, 31)
Affinity DataIC50:  13nMpH: 7.4Assay Description:The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM121427(US8722709, 31)
Affinity DataIC50:  13nMAssay Description:Displacement of TAMRA-labeled dexamethasone from full-length human mineralocorticoid receptor expressed in baculovirus infected insect cells after 60...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM121427(US8722709, 31)
Affinity DataIC50:  44nMAssay Description:Antagonist activity at Gal4-fused human MR LBD expressed in HEK293T cells assessed as inhibition of aldosterone-induced transactivation activity afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed