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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
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Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50108773
(4,5-Dibromo-1H-pyrrole-2-carboxylic acid amide | 4...)
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Affinity Data
IC50: 2.50E+3nM
Assay Description:
Inhibition of MEK1 phosphorylation by activated human recombinant Raf
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
In Depth
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Article
PubMed
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Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50108773
(4,5-Dibromo-1H-pyrrole-2-carboxylic acid amide | 4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+3nM
Assay Description:
Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cystathionine beta-synthase
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50108773
(4,5-Dibromo-1H-pyrrole-2-carboxylic acid amide | 4...)
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Copy InChI
Affinity Data
IC50: 1.56E+5nM
Assay Description:
Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI