Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCyclic AMP-dependent transcription factor ATF-1(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL

LigandBDBM50062674(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)Copy SMILESCopy InChI

Affinity DataIC50:  3.00E+3nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL

LigandBDBM50062674(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)Copy SMILESCopy InChI

Affinity DataIC50:  5.00E+3nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI