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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Aurora kinase A
(Homo sapiens (Human))
Merck Patent
US Patent
Ligand
BDBM116500
(US8637532, 181)
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Affinity Data
IC50: 1.00E+4nM
Assay Description:
The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
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Target
Ribosomal protein S6 kinase beta-1
(Homo sapiens (Human))
Merck Patent
US Patent
Ligand
BDBM116500
(US8637532, 181)
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Affinity Data
IC50: 2.21E+4nM
pH: 7.5 T: 2°C
Assay Description:
P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI