Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50390262(CHEMBL2070416)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of IKKbeta using 5FAM-GRHDSGLDSMK-NH2 as substrate incubated for 10 mins prior to substrate addition by IMAP-TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Mus musculus)
Korea University

Curated by ChEMBL
LigandPNGBDBM50390262(CHEMBL2070416)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of IKKbeta in mouse CIA model spelonocytes assessed as inhibition of TNFalpha production after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50390262(CHEMBL2070416)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MAPK p38betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50390262(CHEMBL2070416)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50390262(CHEMBL2070416)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50390262(CHEMBL2070416)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MAPK p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50390262(CHEMBL2070416)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IKKalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50390262(CHEMBL2070416)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed