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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Cyclin-C
(Homo sapiens (Human))
Genentech
Curated by
ChEMBL
Ligand
BDBM50264866
(4'-(2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin-4-ylo...)
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Affinity Data
IC50: 3nM
Assay Description:
Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase kinase kinase 8
(Homo sapiens (Human))
Abbott Bioresearch Center
Curated by
ChEMBL
Ligand
BDBM50264866
(4'-(2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin-4-ylo...)
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Affinity Data
IC50: 10nM
Assay Description:
Inhibition of human recombinant COT by HTRF-based assay
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase kinase kinase 8
(Homo sapiens (Human))
Abbott Bioresearch Center
Curated by
ChEMBL
Ligand
BDBM50264866
(4'-(2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin-4-ylo...)
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Copy InChI
Affinity Data
IC50: 130nM
Assay Description:
Inhibition of COT (unknown origin) by cell-based HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
Abbott Bioresearch Center
Curated by
ChEMBL
Ligand
BDBM50264866
(4'-(2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin-4-ylo...)
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Copy InChI
Affinity Data
IC50: 1.80E+4nM
Assay Description:
Inhibition of MEK1 (unknown origin) by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI