Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50138137(CHEMBL3754522)Copy SMILESCopy InChI

Affinity DataIC50:  861nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50138137(CHEMBL3754522)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI