Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL

LigandBDBM50320374((E)-4-(4-(2,4-difluorostyryl)phenylsulfonyl)benzam...)Copy SMILESCopy InChI

Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL

LigandBDBM50320374((E)-4-(4-(2,4-difluorostyryl)phenylsulfonyl)benzam...)Copy SMILESCopy InChI

Affinity DataKi:  41nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL

LigandBDBM50320374((E)-4-(4-(2,4-difluorostyryl)phenylsulfonyl)benzam...)Copy SMILESCopy InChI

Affinity DataKi:  7.92E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI