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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Kappa-type opioid receptor
(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50325854
(CHEMBL1223873 | endo-3-((1R,5S)-8-benzyl-8-azabicy...)
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Affinity Data
IC50: 286nM
Assay Description:
Antagonist activity at human kappa opioid receptor expressed in HEK cells assessed as inhibition of dynorphin A-induced [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50325854
(CHEMBL1223873 | endo-3-((1R,5S)-8-benzyl-8-azabicy...)
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Affinity Data
IC50: 610nM
Assay Description:
Inhibition of human ERG by electrophysiology assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mu-type opioid receptor
(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50325854
(CHEMBL1223873 | endo-3-((1R,5S)-8-benzyl-8-azabicy...)
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Affinity Data
IC50: 1.07E+4nM
Assay Description:
Antagonist activity at human mu opioid receptor expressed in HEK cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Delta-type opioid receptor
(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50325854
(CHEMBL1223873 | endo-3-((1R,5S)-8-benzyl-8-azabicy...)
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Copy InChI
Affinity Data
IC50: 2.74E+4nM
Assay Description:
Antagonist activity at human delta opioid receptor expressed in HEK cells assessed as inhibition of SNC-80-induced [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI