Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetAurora kinase A(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM116767(US8637532, 484)
Affinity DataIC50:  4.40nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM116767(US8637532, 484)
Affinity DataIC50:  18nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM116767(US8637532, 484)
Affinity DataIC50:  65nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM116767(US8637532, 484)
Affinity DataIC50:  9.60E+4nMpH: 7.5 T: 2°CAssay Description:The kinase assay is performed as 384-well Flashplate assay (PerkinElmer LAS Germany GmbH). 3.4 nM His6-PDK1(Delta 1-50) (PDK1 that has a His-tag cons...More data for this Ligand-Target Pair
In DepthDetails US Patent