Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50107109((1S,2S,3R)-2-(Amino-carboxy-methyl)-3-(9H-xanthen-...)
Affinity DataKi:  2.70E+3nMAssay Description:Antagonistic activity against stimulation of GTP (gamma) 35 S binding by glutamate in membranes from CHO cells expressing human Metabotropic glutamat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50107109((1S,2S,3R)-2-(Amino-carboxy-methyl)-3-(9H-xanthen-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]glutamate against rat recombinant Metabotropic glutamate receptor 3 expressed in HEK293 c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50107109((1S,2S,3R)-2-(Amino-carboxy-methyl)-3-(9H-xanthen-...)
Affinity DataIC50:  6.40E+3nMAssay Description:Antagonistic activity against stimulation of GTP (gamma) 35 S binding by glutamate in membranes from CHO cells expressing human Metabotropic glutamat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed