Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetArginase-1(Homo sapiens (Human))
Institutes For Pharmaceutical Discovery

Curated by ChEMBL

LigandBDBM50439236(CHEMBL2418997)Copy SMILESCopy InChI

Affinity DataIC50:  210nMAssay Description:Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetArginase-2, mitochondrial(Homo sapiens (Human))
Institutes For Pharmaceutical Discovery

Curated by ChEMBL

LigandBDBM50439236(CHEMBL2418997)Copy SMILESCopy InChI

Affinity DataIC50:  330nMAssay Description:Inhibition of human arginase-2 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI