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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Glutamate receptor ionotropic, kainate 3
(Homo sapiens (Human))
University Walk
Curated by
ChEMBL
Ligand
BDBM50178148
((RS)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl...)
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Affinity Data
Ki: 3.74E+5nM
Assay Description:
Displacement of [3H]kainate from human GLUK7 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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Article
PubMed
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Target
Glutamate receptor ionotropic, kainate 2
(Rattus norvegicus)
University Walk
Curated by
ChEMBL
Ligand
BDBM50178136
((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+6nM
Assay Description:
Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor ionotropic, kainate 2
(Rattus norvegicus)
University Walk
Curated by
ChEMBL
Ligand
BDBM50178137
((R)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+6nM
Assay Description:
Displacement of [3H]kainate from rat GLUK6 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor ionotropic, kainate 2
(Rattus norvegicus)
University Walk
Curated by
ChEMBL
Ligand
BDBM50178148
((RS)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+6nM
Assay Description:
Displacement of [3H]kainate from rat GLUK6 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor ionotropic, kainate 2
(Rattus norvegicus)
University Walk
Curated by
ChEMBL
Ligand
BDBM50178136
((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+6nM
Assay Description:
Displacement of [3H]kainate from rat GLUK6 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor ionotropic, kainate 3
(Homo sapiens (Human))
University Walk
Curated by
ChEMBL
Ligand
BDBM50178136
((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.00E+3nM
Assay Description:
Antagonist activity at recombinant GluK3 receptor (unknown origin) expressed in Xenopus oocyte assessed as inhibition of glutamate-induced current am...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor ionotropic, kainate 2
(Homo sapiens (Human))
University Walk
Curated by
ChEMBL
Ligand
BDBM50178136
((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+5nM
Assay Description:
Antagonist activity at human recombinant GLUK6 expressed in HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Glutamate receptor 2
(Homo sapiens (Human))
University Walk
Curated by
ChEMBL
Ligand
BDBM50178136
((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+5nM
Assay Description:
Antagonist activity at human recombinant GLUA2-AMPA receptor expressed in HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor ionotropic, kainate 3
(Homo sapiens (Human))
University Walk
Curated by
ChEMBL
Ligand
BDBM50178148
((RS)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.80E+5nM
Assay Description:
Displacement of [3H]kainate from human GLUK7 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor ionotropic, kainate 1
(RAT)
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50178136
((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...)
Copy SMILES
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Affinity Data
Kd: 3.94E+3nM
Assay Description:
Displacement of [3H]S-glutamate from rat GluR5 S1S2 ligand binding core expressed in Escherichia coli (DE3)
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Glutamate receptor ionotropic, kainate 1
(RAT)
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50178137
((R)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+5nM
Assay Description:
Antagonism on GLUK5 containing kainate induced deploarization of isolated neonatal rat dorsal root C-fibers
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor 2
(Rattus norvegicus)
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50178136
((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.46E+5nM
Assay Description:
Displacement of [3H]AMPA from wild type rat GluR2 S1S2 ligand binding core
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor ionotropic, kainate 5
(Rattus norvegicus)
University Walk
Curated by
ChEMBL
Ligand
BDBM50178136
((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 402nM
Assay Description:
Antagonist activity against GLUK5-containing kainate receptor by inhibition of kainate-induced depolarization of neonatal rat dorsal root fibers
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor ionotropic, kainate 1
(RAT)
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50178136
((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 402nM
Assay Description:
Activity at native GLUK5 kainate receptor assessed as antagonism of kainite-induced depolarization of neonatal anaesthetised rat dorsal root fibres
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Glutamate receptor ionotropic, kainate 1
(RAT)
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50178136
((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 402nM
Assay Description:
Antagonism on GLUK5 containing kainate induced deploarization of isolated neonatal rat dorsal root C-fibers
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Glutamate receptor ionotropic, kainate 1
(RAT)
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50178148
((RS)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.09E+3nM
Assay Description:
Antagonism on GLUK5 containing kainate induced deploarization of isolated neonatal rat dorsal root C-fibers
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI