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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM8580((2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2...)
Affinity DataKi:  4.29E+4nM ΔG°:  -24.9kJ/moleT: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM8580((2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2...)
Affinity DataKi:  4.29E+4nM ΔG°:  -24.7kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Rev(Human immunodeficiency virus 1)
Graduate School Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM8580((2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibitory activity against peptide binding to the RRE RNA was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Rev(Human immunodeficiency virus 1)
Graduate School Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM8580((2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of [3H]Rev response element binding to HIV1 biotinylated-Rev protein expressed in Escherichia coli after 15 mins by scintillation proximit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Tat(Human immunodeficiency virus type 1 (isolate PCV12...)
Graduate School Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM8580((2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of Tat peptide binding to HIV-1 TAR RNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLecithin retinol acyltransferase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM8580((2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2...)
Affinity DataIC50:  3.86E+4nMAssay Description:Compound tested in vitro for inhibition of translation using highly active Escherichia coli S30 and a plasmid containing a gene expressing truncated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLecithin retinol acyltransferase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM8580((2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2...)
Affinity DataIC50:  3.86E+4nMAssay Description:Compound tested in vitro for inhibition of translation using highly active Escherichia coli S30 and a plasmid containing a gene expressing truncated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLecithin retinol acyltransferase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM8580((2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2...)
Affinity DataIC50:  1.02E+5nMAssay Description:Compound tested in vitro for inhibition of translation using highly active Escherichia coli S30 and a plasmid containing a gene expressing truncated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLecithin retinol acyltransferase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM8580((2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2...)
Affinity DataIC50:  1.02E+5nMAssay Description:Compound tested in vitro for inhibition of translation using highly active Escherichia coli S30 and a plasmid containing a gene expressing truncated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed