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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM220885(US9302986, 9)
Affinity DataIC50: <1.00E+3nMpH: 7.4 T: 2°CAssay Description:Recombinant human DAO (2.4 μg/mL) was used as source of DAO enzyme activities. The assay was performed as described in the method for human SSAO/V...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM220885(US9302986, 9)
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:Recombinant human MAO-B (0.06 mg/mL; Sigma Aldrich) was used as source of MAO-B enzyme activities. The assay was performed in a similar way as for hu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Rattus norvegicus (Rat))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM220885(US9302986, 9)
Affinity DataIC50: <1.00E+5nMpH: 7.4Assay Description:Abdominal fat from BALB/c mice, Wistar or Sprague Dawley rats, which are tissues enriched with SSAO/VAP-1-were surgically removed. For every gram of ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM220885(US9302986, 9)
Affinity DataIC50: <1.00E+5nMpH: 7.4Assay Description:Briefly, HMEC cell expressing human SSAO/VAP-1 were grown in several 10 cm petri dishes, once the cells reached 100% confluency, cells were harvested...More data for this Ligand-Target Pair
In DepthDetails US Patent