Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 96 hits in this display   

TargetMetabotropic glutamate receptor 1(RAT)
Johnson And Johnson Pharmaceutical Research And Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM86212(1S, 3R-ACPD | CAS_104766 | NSC_104766)
Affinity DataKi:  1.92nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi:  9.33nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi:  2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi:  2.10E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi:  3.20E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi:  5.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataKi:  5.00E+3nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate metabotropic receptor 5(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi:  5.30E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi:  5.40E+3nMMore data for this Ligand-Target Pair
TargetGlutamate metabotropic receptor 5(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi:  6.70E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi:  8.00E+3nMMore data for this Ligand-Target Pair
TargetGlutamate metabotropic receptor 1(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi:  9.30E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(RAT)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Johnson And Johnson Pharmaceutical Research And Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM86212(1S, 3R-ACPD | CAS_104766 | NSC_104766)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate metabotropic receptor 5(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM50060133((1R,3R)-1-Amino-cyclopentane-1,3-dicarboxylic acid...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate metabotropic receptor 5(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate metabotropic receptor 5(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate metabotropic receptor 5(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate metabotropic receptor 5(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM50060133((1R,3R)-1-Amino-cyclopentane-1,3-dicarboxylic acid...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate metabotropic receptor 5(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate metabotropic receptor 5(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate metabotropic receptor 5(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate metabotropic receptor 1(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM50060133((1R,3R)-1-Amino-cyclopentane-1,3-dicarboxylic acid...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate metabotropic receptor 1(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate metabotropic receptor 1(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataKi:  1.50E+4nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataKi:  4.20E+4nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataKi:  4.50E+4nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 8 (mGluR-8).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataKi:  6.00E+4nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 6 (mGluR-6).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataKi:  9.80E+4nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVesicular glutamate transporter 3(Rattus norvegicus)
The University Of Montana

Curated by ChEMBL
LigandPNGBDBM50060136((1R,3S)-1-Amino-cyclopentane-1,3-dicarboxylic acid...)
Affinity DataKi:  7.00E+5nMAssay Description:Evaluated for competitive inhibition against Vesicular glutamate transporter (VGLUT), and Ki value was reported.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataKi: >1.00E+6nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 7 (mGluR-7).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 11(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  2.20E+4nMAssay Description:Effective concentration of the compound for half maximal stimulation of PI hydrolysis (mGluR1a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Johnson And Johnson Pharmaceutical Research And Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50: >1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1b in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Johnson And Johnson Pharmaceutical Research And Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  1.30E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1c in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  5.00E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR2 in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Johnson And Johnson Pharmaceutical Research And Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  5.00E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1a in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  3.90E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  9.30E+3nMAssay Description:Agonist activity against Metabotropic glutamate receptor 1 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50: >3.00E+5nMAssay Description:Agonist activity against Metabotropic glutamate receptor 1 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50060136((1R,3S)-1-Amino-cyclopentane-1,3-dicarboxylic acid...)
Affinity DataEC50:  1.27E+5nMAssay Description:Agonist activity against Metabotropic glutamate receptor 1 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50060133((1R,3R)-1-Amino-cyclopentane-1,3-dicarboxylic acid...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity against Metabotropic glutamate receptor 1 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  1.80E+4nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity against Metabotropic glutamate receptor 4 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50:  1.30E+4nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50:  4.80E+4nMAssay Description:Agonist activity against Metabotropic glutamate receptor 4 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50060136((1R,3S)-1-Amino-cyclopentane-1,3-dicarboxylic acid...)
Affinity DataEC50:  1.10E+5nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50060136((1R,3S)-1-Amino-cyclopentane-1,3-dicarboxylic acid...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity against Metabotropic glutamate receptor 4 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50060133((1R,3R)-1-Amino-cyclopentane-1,3-dicarboxylic acid...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity against Metabotropic glutamate receptor 2 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  5.00E+4nMAssay Description:Agonistic activity against phospholipase C (PLC) was determined in adult rat hippocampal slicesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  3.90E+4nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  2.00E+3nMAssay Description:Activity of the compound tested at cloned rat mGluR2 receptor expressed in Chinese Hamster Ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  2.30E+4nMAssay Description:Activity of the compound tested at cloned rat Metabotropic glutamate receptor 5 expressed in Chinese Hamster Ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Johnson And Johnson Pharmaceutical Research And Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  1.50E+4nMAssay Description:Activity of the compound tested at cloned rat Metabotropic glutamate receptor 1 expressed in Chinese Hamster Ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  8.00E+5nMAssay Description:Activity of the compound tested at cloned rat Metabotropic glutamate receptor 4 expressed in Chinese Hamster Ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  6.00E+4nMAssay Description:Tested for the agonistic activity against Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails Article
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  1.50E+4nMAssay Description:Tested for the agonistic activity against Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
TargetMetabotropic glutamate receptor 1(RAT)
Johnson And Johnson Pharmaceutical Research And Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  4.20E+4nMAssay Description:Tested for the agonistic activity against Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  3.00E+4nMAssay Description:Agonistic activity evaluated in CHO(Chinese hamster ovary) cells expressing chimeric mGluR3/1a receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  1.21E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR2 in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50: >1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR7 in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Johnson And Johnson Pharmaceutical Research And Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  1.05E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1b in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  1.66E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50: >2.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR6 in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Cns Research

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50: >1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR7 in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  3.90E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  5.00E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5a in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  5.00E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR2 in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Cns Research

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  8.00E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR3 in ratMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Mus musculus)
Cns Research

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR8 in mouseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Cns Research

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50:  3.00E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 3 (mGluR3)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50: >3.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50:  1.30E+4nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  2.00E+3nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50: >3.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  8.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50:  5.00E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  8.20E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  1.50E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  2.30E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre

Curated by PDSP Ki Database
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50: >1.00E+5nMAssay Description:Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre

Curated by PDSP Ki Database
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50: >1.00E+5nMAssay Description:Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  5.00E+3nMAssay Description:Tested for the agonistic activity against Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonistic activity evaluated in CHO(Chinese hamster ovary) cells expressing mGluR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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