Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM239007(US9403846, 21)
Affinity DataIC50:  302nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM238983(US9403846, 1)
Affinity DataIC50:  447nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2 [21-466](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM238983(US9403846, 1)
Affinity DataIC50:  1.29E+3nMpH: 4.5 T: 2°CAssay Description:A synthetic substrate that can be cleaved by BACE2 having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Green at the Cy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent