Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50300716(8-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-8-(3-(2-f...)Copy SMILESCopy InChI

Affinity DataIC50:  740nMAssay Description:Inhibition of human BACE1 by FRETMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50300716(8-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-8-(3-(2-f...)Copy SMILESCopy InChI

Affinity DataIC50:  9.53E+4nMAssay Description:Inhibition of human cathepsin D by FRETMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI