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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50308178
(1-{3-[(5-Chloro-1-naphthyl)sulfonyl]-1H-indazol-5-...)
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Affinity Data
Ki: 4.52nM
Assay Description:
Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50308178
(1-{3-[(5-Chloro-1-naphthyl)sulfonyl]-1H-indazol-5-...)
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Copy InChI
Affinity Data
Ki: 78nM
Assay Description:
Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50308178
(1-{3-[(5-Chloro-1-naphthyl)sulfonyl]-1H-indazol-5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 70.1nM
Assay Description:
Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP formation by RIA
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI