Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50334720
(3-Amino-N-[3-(naphthalen-1-sulfonyl)-1H-indazol-5-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.5nM
Assay Description:
Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50334720
(3-Amino-N-[3-(naphthalen-1-sulfonyl)-1H-indazol-5-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 344nM
Assay Description:
Binding affinity to 5-HT2B receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50334720
(3-Amino-N-[3-(naphthalen-1-sulfonyl)-1H-indazol-5-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 573nM
Assay Description:
Binding affinity to 5-HT2C receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50334720
(3-Amino-N-[3-(naphthalen-1-sulfonyl)-1H-indazol-5-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >5.00E+3nM
Assay Description:
Binding affinity to 5-HT1B receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50334720
(3-Amino-N-[3-(naphthalen-1-sulfonyl)-1H-indazol-5-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >5.00E+3nM
Assay Description:
Binding affinity to 5-HT1D receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 7
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50334720
(3-Amino-N-[3-(naphthalen-1-sulfonyl)-1H-indazol-5-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >5.00E+3nM
Assay Description:
Binding affinity to 5-HT7 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-2A adrenergic receptor
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50334720
(3-Amino-N-[3-(naphthalen-1-sulfonyl)-1H-indazol-5-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >5.00E+3nM
Assay Description:
Binding affinity to adrenergic alpha2A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50334720
(3-Amino-N-[3-(naphthalen-1-sulfonyl)-1H-indazol-5-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >5.00E+3nM
Assay Description:
Binding affinity to dopamine D2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50334720
(3-Amino-N-[3-(naphthalen-1-sulfonyl)-1H-indazol-5-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >5.00E+3nM
Assay Description:
Binding affinity to 5-HT1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50334720
(3-Amino-N-[3-(naphthalen-1-sulfonyl)-1H-indazol-5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.80nM
Assay Description:
Antagonist activity at cloned human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced cyclic AMP formation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI