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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Prothrombin
(Homo sapiens (Human))
Curacyte Discovery
Curated by
ChEMBL
Ligand
BDBM50254313
((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(3...)
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Affinity Data
Ki: 51nM
Assay Description:
Inhibition of thrombin (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Suppressor of tumorigenicity 14 protein
(Homo sapiens (Human))
The Medicines Company (Leipzig)
US Patent
Ligand
BDBM104901
(US8569313, Inhibitor 8)
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Affinity Data
Ki: 91nM
Assay Description:
Inhibition assay using matriptase enzyme
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
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Target
Suppressor of tumorigenicity 14 protein
(Homo sapiens (Human))
The Medicines Company (Leipzig)
US Patent
Ligand
BDBM50254313
((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(3...)
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Copy InChI
Affinity Data
Ki: 91nM
Assay Description:
Inhibition of matriptase (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Plasminogen
(Homo sapiens (Human))
Curacyte Discovery
Curated by
ChEMBL
Ligand
BDBM50254313
((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(3...)
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Affinity Data
Ki: 334nM
Assay Description:
Inhibition of plasmin (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Curacyte Discovery
Curated by
ChEMBL
Ligand
BDBM50254313
((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(3...)
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Affinity Data
Ki: 5.60E+3nM
Assay Description:
Inhibition of factor 10a (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Urokinase-type plasminogen activator
(Homo sapiens (Human))
Curacyte Discovery
Curated by
ChEMBL
Ligand
BDBM50254313
((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(3...)
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Affinity Data
Ki: 1.20E+4nM
Assay Description:
Inhibition of uPA (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI