Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetProthrombin(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254313((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(3...)
Affinity DataKi:  51nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM104901(US8569313, Inhibitor 8)
Affinity DataKi:  91nMAssay Description:Inhibition assay using matriptase enzymeMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM50254313((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(3...)
Affinity DataKi:  91nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254313((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(3...)
Affinity DataKi:  334nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254313((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(3...)
Affinity DataKi:  5.60E+3nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254313((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(3...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed