Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Urokinase-type plasminogen activator
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50147093
(6-Carbamimidoyl-4-(pyrimidin-2-ylamino)-naphthalen...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.620nM
Assay Description:
Binding affinity towards Urokinase-type plasminogen activator (urokinase)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Urokinase-type plasminogen activator
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50147093
(6-Carbamimidoyl-4-(pyrimidin-2-ylamino)-naphthalen...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.631nM
Assay Description:
Inhibition of urokinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Serine protease 1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50147093
(6-Carbamimidoyl-4-(pyrimidin-2-ylamino)-naphthalen...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 20nM
Assay Description:
Binding affinity against trypsin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kallikrein-1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50147093
(6-Carbamimidoyl-4-(pyrimidin-2-ylamino)-naphthalen...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 40nM
Assay Description:
Binding affinity towards P-kallikrein
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Plasminogen
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50147093
(6-Carbamimidoyl-4-(pyrimidin-2-ylamino)-naphthalen...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 150nM
Assay Description:
Binding affinity against plasmin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tissue-type plasminogen activator
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50147093
(6-Carbamimidoyl-4-(pyrimidin-2-ylamino)-naphthalen...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 680nM
Assay Description:
Binding affinity towards tissue type plasminogen activator
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50147093
(6-Carbamimidoyl-4-(pyrimidin-2-ylamino)-naphthalen...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 940nM
Assay Description:
Binding affinity against thrombin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Urokinase-type plasminogen activator
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50147093
(6-Carbamimidoyl-4-(pyrimidin-2-ylamino)-naphthalen...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.620nM
Assay Description:
Inhibition of uPA (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI