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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Coagulation factor X
(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by
ChEMBL
Ligand
BDBM50135945
(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
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Affinity Data
Ki: 0.910nM
Assay Description:
Inhibition of factor 10a
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
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Target
Coagulation factor X
(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by
ChEMBL
Ligand
BDBM50135945
(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.910nM
Assay Description:
Tested in vitro for inhibition of human Coagulation factor X
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by
ChEMBL
Ligand
BDBM50135945
(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
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Copy InChI
Affinity Data
Ki: 2.90nM
Assay Description:
Tested in vitro for inhibition of rabbit Coagulation factor X
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Plasma kallikrein
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50135945
(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
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Affinity Data
Ki: 58nM
Assay Description:
Tested in vitro for inhibition of human plasma Kallikriene
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine protease 1
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50135945
(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
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Affinity Data
Ki: 3.50E+3nM
Assay Description:
Tested in vitro for inhibition of human trypsin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50135945
(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
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Affinity Data
Ki: 3.60E+3nM
Assay Description:
In vitro for inhibition of human thrombin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50135945
(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.60E+3nM
Assay Description:
Inhibition of thrombin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vitamin K-dependent protein C
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50135945
(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
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Affinity Data
Ki: 4.60E+3nM
Assay Description:
Tested in vitro for inhibition of human activated protein C
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Chymotrypsinogen A
(Bos taurus (bovine))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50135945
(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
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Affinity Data
Ki: 6.80E+3nM
Assay Description:
Tested in vitro for inhibition of human Chymotrypsinogen
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor IX
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50135945
(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
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Affinity Data
Ki: >1.20E+4nM
Assay Description:
Tested in vitro for inhibition of human Coagulation factor IX
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Urokinase-type plasminogen activator
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50135945
(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
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Affinity Data
Ki: >1.30E+4nM
Assay Description:
Tested in vitro for inhibition of human Urokinase-type plasminogen activator
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor VII
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50135945
(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.50E+4nM
Assay Description:
Tested in vitro for inhibition of human Coagulation factor VIIa
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Plasminogen
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50135945
(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.50E+4nM
Assay Description:
Tested in vitro for inhibition of human plasmin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tissue-type plasminogen activator
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50135945
(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >3.30E+4nM
Assay Description:
Tested in vitro for inhibition of human Tissue type plasminogen activator
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI