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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 14 hits in this display   

TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50135945(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Affinity DataKi:  0.910nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50135945(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Affinity DataKi:  0.910nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50135945(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Affinity DataKi:  2.90nMAssay Description:Tested in vitro for inhibition of rabbit Coagulation factor XMore data for this Ligand-Target Pair
TargetPlasma kallikrein(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135945(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Affinity DataKi:  58nMAssay Description:Tested in vitro for inhibition of human plasma KallikrieneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135945(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Affinity DataKi:  3.50E+3nMAssay Description:Tested in vitro for inhibition of human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135945(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Affinity DataKi:  3.60E+3nMAssay Description:In vitro for inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135945(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135945(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Affinity DataKi:  4.60E+3nMAssay Description:Tested in vitro for inhibition of human activated protein CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135945(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Affinity DataKi:  6.80E+3nMAssay Description:Tested in vitro for inhibition of human ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135945(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Affinity DataKi: >1.20E+4nMAssay Description:Tested in vitro for inhibition of human Coagulation factor IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135945(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Affinity DataKi: >1.30E+4nMAssay Description:Tested in vitro for inhibition of human Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135945(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Affinity DataKi: >1.50E+4nMAssay Description:Tested in vitro for inhibition of human Coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135945(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Affinity DataKi: >1.50E+4nMAssay Description:Tested in vitro for inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135945(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)
Affinity DataKi: >3.30E+4nMAssay Description:Tested in vitro for inhibition of human Tissue type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed