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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Metallo-beta-lactamase type 2
(Klebsiella pneumoniae)
Merck Sharp & Dohme
US Patent
Ligand
BDBM262622
(3-(1H-pyrrolo[3,2-b]pyridin-6-yl)-2- (1H-tetrazol-...)
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Affinity Data
IC50: 0.523nM
pH: 7.0
Assay Description:
The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
VIM-1 metallo-beta-lactamase
(Klebsiella pneumoniae)
Merck Sharp & Dohme
US Patent
Ligand
BDBM262622
(3-(1H-pyrrolo[3,2-b]pyridin-6-yl)-2- (1H-tetrazol-...)
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Copy InChI
Affinity Data
IC50: 0.549nM
pH: 7.0
Assay Description:
The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Metallo-beta-lactamase type 2
(Serratia marcescens)
Merck Sharp & Dohme
US Patent
Ligand
BDBM262622
(3-(1H-pyrrolo[3,2-b]pyridin-6-yl)-2- (1H-tetrazol-...)
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Copy InChI
Affinity Data
IC50: 3.91nM
pH: 7.0
Assay Description:
The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI