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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Ligand
BDBM16661
(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
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Affinity Data
Ki: 9nM
Assay Description:
Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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Target
Carbonic anhydrase 4
(Bos taurus (bovine))
Universita Degli Studi Di Firenze
Ligand
BDBM16661
(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
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Affinity Data
Ki: 15nM
Assay Description:
Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC sid
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Article
PubMed
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Target
Carbonic anhydrase 5A, mitochondrial
(Mus musculus (mouse))
Universita Degli Studi Di Firenze
Ligand
BDBM16661
(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
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Affinity Data
Ki: 20nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
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Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universita Degli Studi Di Firenze
Ligand
BDBM16661
(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
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Affinity Data
Ki: 40nM
Assay Description:
Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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Article
PubMed
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Target
Alkaline phosphatase, tissue-nonspecific isozyme
(Bos taurus (Cattle))
Forman Christian College (A Chartered University)
Curated by
ChEMBL
Ligand
BDBM16661
(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
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Affinity Data
Ki: 1.39E+3nM
Assay Description:
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
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In Depth
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Article
PubMed
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Target
Carbonic anhydrase 2
(Bos taurus)
Forman Christian College (A Chartered University)
Curated by
ChEMBL
Ligand
BDBM16661
(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
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Affinity Data
IC50: 100nM
Assay Description:
Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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In Depth
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Article
PubMed
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Target
Intestinal-type alkaline phosphatase
(Bos taurus (Cattle))
Forman Christian College (A Chartered University)
Curated by
ChEMBL
Ligand
BDBM16661
(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
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Affinity Data
IC50: 1.13E+3nM
Assay Description:
Inhibition of calf intestinal alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectrophotometric...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Alkaline phosphatase, tissue-nonspecific isozyme
(Bos taurus (Cattle))
Forman Christian College (A Chartered University)
Curated by
ChEMBL
Ligand
BDBM16661
(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.26E+3nM
Assay Description:
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI