Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetCarboxylic ester hydrolase(Equus caballus (Horse))
TBA

Curated by ChEMBL
LigandPNGBDBM50060470(10-azatetracyclo[10.2.1.02,11.04,9]pentadeca-2,4,6...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of (BChE) Butyrylcholinesterase of horse serumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
TBA

Curated by ChEMBL
LigandPNGBDBM50060470(10-azatetracyclo[10.2.1.02,11.04,9]pentadeca-2,4,6...)
Affinity DataIC50:  12nMAssay Description:Inhibition of acetylcholinesterase (AChE) in electric eel (type V-S) by modified radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50060470(10-azatetracyclo[10.2.1.02,11.04,9]pentadeca-2,4,6...)
Affinity DataIC50:  32nMAssay Description:Inhibition of acetylcholinesterase (AChE) of human red blood cell (type XIII) by modified radiometric AChE assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50060470(10-azatetracyclo[10.2.1.02,11.04,9]pentadeca-2,4,6...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibitory activity against human erythrocyte acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060470(10-azatetracyclo[10.2.1.02,11.04,9]pentadeca-2,4,6...)
Affinity DataIC50:  41nMAssay Description:In vitro inhibition of Butyrylcholinesterase from human plasma.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060470(10-azatetracyclo[10.2.1.02,11.04,9]pentadeca-2,4,6...)
Affinity DataIC50:  200nMAssay Description:Inhibition of neuronal uptake of 5 - Hydroxytryptamine in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060470(10-azatetracyclo[10.2.1.02,11.04,9]pentadeca-2,4,6...)
Affinity DataIC50:  240nMAssay Description:In vitro inhibition of acetylcholinesterase, isolated from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50060470(10-azatetracyclo[10.2.1.02,11.04,9]pentadeca-2,4,6...)
Affinity DataIC50:  240nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50060470(10-azatetracyclo[10.2.1.02,11.04,9]pentadeca-2,4,6...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of neuronal uptake of Noradrenaline in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed