Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Synovo

US Patent
LigandPNGBDBM50379219(CHEMBL2011303 | US9416123, 19)
Affinity DataIC50:  8.70E+4nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Synovo

US Patent
LigandPNGBDBM50379219(CHEMBL2011303 | US9416123, 19)
Affinity DataIC50:  8.70E+4nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza

Curated by ChEMBL
LigandPNGBDBM50379219(CHEMBL2011303 | US9416123, 19)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Synovo

US Patent
LigandPNGBDBM50379219(CHEMBL2011303 | US9416123, 19)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza

Curated by ChEMBL
LigandPNGBDBM50379219(CHEMBL2011303 | US9416123, 19)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails US Patent