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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Mitogen-activated protein kinase kinase kinase 8
(Homo sapiens (Human))
Abbott Bioresearch Center
Curated by
ChEMBL
Ligand
BDBM50264741
(4'-(2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin-4-ylo...)
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Affinity Data
IC50: 230nM
Assay Description:
Inhibition of human recombinant COT by HTRF-based assay
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
Abbott Bioresearch Center
Curated by
ChEMBL
Ligand
BDBM50264741
(4'-(2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin-4-ylo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.50E+3nM
Assay Description:
Inhibition of MEK1 (unknown origin) by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI