Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011760(1-(4-Amino-phenyl)-3-aza-bicyclo[3.1.0]hexane-2,4-...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human placental cytochrome P450 19A1 androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011763(1-(4-Amino-phenyl)-3-aza-bicyclo[3.1.0]hexane-2,4-...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011760(1-(4-Amino-phenyl)-3-aza-bicyclo[3.1.0]hexane-2,4-...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011757(1-(4-Amino-phenyl)-3-aza-bicyclo[3.1.0]hexane-2,4-...)
Affinity DataIC50:  7.77E+5nMAssay Description:In vitro inhibition of cytochrome P450 19A1 AromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM50011760(1-(4-Amino-phenyl)-3-aza-bicyclo[3.1.0]hexane-2,4-...)
Affinity DataKd: >3.00E+4nMAssay Description:Measuring compound ligand binding to CRBN-DDB1 was carried out using an established sensitive and quantitative in vitro fluorescence polarization (FP...More data for this Ligand-Target Pair
In DepthDetails US Patent