Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 96 hits in this display   

TargetCarbonic anhydrase 13(Mus musculus (mouse))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  1.30nMAssay Description:Inhibitory activity against murine carbonic anhydrase XIII (mCA XIII) by using CO2 hydrase assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Mus musculus (mouse))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  1.90nMAssay Description:Ki value against murine carbonic anhydrase XIIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  4.5nMAssay Description:Ki value against human carbonic anhydrase XII (hCA XII)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  4.5nMAssay Description:Inhibitory constant against catalytic domain of human carbonic anhydrase XIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  6.5nMAssay Description:Ki value against human carbonic anhydrase VIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Sulfurihydrogenibium sp. (strain YO3AOP1))
Universit£

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  9.70nMAssay Description:Inhibition of recombinant Sulfurihydrogenibium yellowstonense YO3AOP1 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Astrosclera willeyana)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  16nMAssay Description:Inhibition of GST-tagged astrosclera willeyana Astrosclerin-3 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Stylophora pistillata)
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  19.7nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Stylophora pistillata)
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  19.7nMAssay Description:Inhibition of cloned Stylophora pistillata alpha-CA expressed in human HEK293 cells by stopped-flow CO2 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  24nMAssay Description:Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  24nMAssay Description:Inhibitory constant against catalytic domain of human carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  24nMAssay Description:Inhibitory constant against human Carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against human carbonic anhydrase IX (hCA IX) by using CO2 hydrase assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  24nMAssay Description:Inhibition of catalytic domain of human recombinant CA IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  24nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  24nMAssay Description:Inhibition of full length human recombinant CA VIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase isozyme IX, by CO2 hydrase assay method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against human tumor-associated transmembrane carbonic anhydrase IX.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  30nMAssay Description:Inhibitory activity against human carbonic anhydrase II (hCA II) by using esterase assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  30nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  30nMAssay Description:Inhibition of human carbonic anhydrase-2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  30nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  30nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  30nMAssay Description:Inhibition of human recombinant Carbonic anhydrase 2 compound preincubated for 15 mins by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  30nMAssay Description:Inhibition of human carbonic anhydrase 2 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  30nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  30nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  30nMAssay Description:Inhibitory constant against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  30nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  30nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  42nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Anopheles gambiae)
University Of Tampere And Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  47nMAssay Description:Inhibition of Anopheles gambiae carbonic anhydrase pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant cytosolic isozyme CA II by stopped-flow CO2 hydrase methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMAssay Description:Ki value against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMAssay Description:Ki value against human carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant CA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 2 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase II by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMAssay Description:Inhibition of recombinant human carbonic anhydrase-2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 15 [19-324](Mus musculus (mouse))
University Of Tampere

LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  63nM ΔG°:  -40.4kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universit£

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  72nMAssay Description:Inhibitory activity against bovine carbonic anhydrase isozyme IV isolated from bovine lung microsomes, by esterase assay method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  76nMAssay Description:Inhibitory constant against human carbonic anhydrase XIV in CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  95nMAssay Description:Inhibition of human carbonic anhydrase-1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  95nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  95nMAssay Description:Inhibition of human recombinant Carbonic anhydrase 2 compound preincubated for 15 mins by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  95nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  95nMAssay Description:Inhibitory constant against human Carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  95nMAssay Description:Inhibition of human carbonic anhydrase 1 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  95nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase isozyme I by esterase assay method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  95nMAssay Description:Inhibitory activity against human carbonic anhydrase I (hCA I) by using esterase assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  95nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  95nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  95nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Helicobacter pylori (strain G27))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  96nMAssay Description:Inhibition of Helicobacter pylori recombinant CAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCARBONIC ANHYDRASE(Helicobacter pylori J99)
Kochi Medical School

LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  114nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  121nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  125nMAssay Description:Inhibition of human carbonic anhydrase-2 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  125nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  125nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Tampere

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  125nMAssay Description:Inhibition of human Carbonic anhydrase2 using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Saccharomyces cerevisiae)
Balikesir University

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  154nMAssay Description:Inhibition of Saccharomyces cerevisiae recombinant CA expressed in Escherichia coli by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis)
Kochi Medical School

LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  170nM ΔG°:  -38.0kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis)
Universit£

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  170nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv3273 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  185nMAssay Description:Inhibition of human recombinant cytosolic isozyme CA I by stopped-flow CO2 hydrase methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  185nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  185nMAssay Description:Ki value against human carbonic anhydrase I (hCA I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  185nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  185nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase I by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  185nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 1 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  185nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  185nMAssay Description:Inhibition of human recombinant CA1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  185nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  185nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  185nMAssay Description:Inhibition of recombinant human carbonic anhydrase-1 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  185nMAssay Description:Ki value against human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase, alpha family(Thiomicrospira crunogena (strain XCL-2))
Universit£

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  402nMAssay Description:Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Cryptococcus neoformans var. grubii (Filobasidiell...)
Universite Degli Studi Di Firenze

LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  624nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Candida albicans (Yeast))
Universite Degli Studi Di Firenze

LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  727nM ΔG°:  -34.4kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Universit£

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  853nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv1284 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Universit£

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  853nM ΔG°:  -34.1kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta carbonic anhydrase(Thalassiosira weissflogii)
Universit£

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  862nMAssay Description:Inhibition of Thalassiosira weissflogii delta carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Stylophora pistillata)
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  902nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis)
Universit£

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  2.29E+3nMAssay Description:Inhibition of full length Mycobacterium tuberculosis H37Rv recombinant carbonic anhydrase 2 encoded by RV3588c by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  2.40E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  2.40E+4nMAssay Description:Inhibition of human Carbonic anhydrase1 using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  2.40E+4nMAssay Description:Inhibition of human carbonic anhydrase-1 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  2.40E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Kochi Medical School

Curated by ChEMBL
LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  1.40E+5nMAssay Description:Inhibition of human recombinant CA 3 assessed as CO2 hydration by stopped flow kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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