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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Steroid 17-alpha-hydroxylase/17,20 lyase
(Homo sapiens (Human))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50322783
(4'-(pyridin-4-ylmethyl)biphenyl-3-amine | CHEMBL11...)
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Affinity Data
IC50: 226nM
Assay Description:
Inhibition of human CYP17 expressed in Escherichia coli
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Steroid 17-alpha-hydroxylase/17,20 lyase
(Homo sapiens (Human))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50322783
(4'-(pyridin-4-ylmethyl)biphenyl-3-amine | CHEMBL11...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 226nM
Assay Description:
Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductase
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50322783
(4'-(pyridin-4-ylmethyl)biphenyl-3-amine | CHEMBL11...)
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Affinity Data
IC50: 287nM
Assay Description:
Inhibition of human CYP11B1 expressed in hamster V79MZh cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50322783
(4'-(pyridin-4-ylmethyl)biphenyl-3-amine | CHEMBL11...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 287nM
Assay Description:
Inhibition of human CYP11B1 expressed in hamster fibroblast
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50322783
(4'-(pyridin-4-ylmethyl)biphenyl-3-amine | CHEMBL11...)
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Copy InChI
Affinity Data
IC50: 921nM
Assay Description:
Inhibition of human CYP11B2 expressed in hamster fibroblast
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50322783
(4'-(pyridin-4-ylmethyl)biphenyl-3-amine | CHEMBL11...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 921nM
Assay Description:
Inhibition of human CYP11B2 expressed in hamster V79MZh cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50322783
(4'-(pyridin-4-ylmethyl)biphenyl-3-amine | CHEMBL11...)
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Affinity Data
IC50: 1.52E+3nM
Assay Description:
Inhibition of CYP3A4 expressed in baculovirus infected insect microsomes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50322783
(4'-(pyridin-4-ylmethyl)biphenyl-3-amine | CHEMBL11...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.52E+3nM
Assay Description:
Inhibition of recombinant CYP3A4 expressed in baculovirus-infected insect microsome
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aromatase
(Homo sapiens (Human))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50322783
(4'-(pyridin-4-ylmethyl)biphenyl-3-amine | CHEMBL11...)
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Affinity Data
IC50: 2.83E+3nM
Assay Description:
Inhibition of CYP19 in human placental microsomes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aromatase
(Homo sapiens (Human))
Saarland University
Curated by
ChEMBL
Ligand
BDBM50322783
(4'-(pyridin-4-ylmethyl)biphenyl-3-amine | CHEMBL11...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.83E+3nM
Assay Description:
Inhibition of human placental CYP19
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI