Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207492(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-cyclopenty...)
Affinity DataIC50:  39nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207492(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-cyclopenty...)
Affinity DataIC50:  153nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50207492(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-cyclopenty...)
Affinity DataIC50:  850nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50207492(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-cyclopenty...)
Affinity DataIC50:  850nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed