Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAdenosine receptor A2b(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL

LigandBDBM50313076(6-(furan-2-yl)-5-(pyrimidin-4-yl)-1H-pyrazolo[3,4-...)Copy SMILESCopy InChI

Affinity DataKi:  8nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 60 mins by filtration binding assayMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAdenosine receptor A1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL

LigandBDBM50313076(6-(furan-2-yl)-5-(pyrimidin-4-yl)-1H-pyrazolo[3,4-...)Copy SMILESCopy InChI

Affinity DataKi:  357nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 90 mins by filtration binding assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAdenosine receptor A2a(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL

LigandBDBM50313076(6-(furan-2-yl)-5-(pyrimidin-4-yl)-1H-pyrazolo[3,4-...)Copy SMILESCopy InChI

Affinity DataKi:  858nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI