Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Pharma

Curated by ChEMBL

LigandBDBM50116038(4-(4-Benzofuran-2-yl-5-pyridin-4-yl-1H-imidazol-2-...)Copy SMILESCopy InChI

Affinity DataIC50:  5nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Novartis Pharma

Curated by ChEMBL

LigandBDBM50116038(4-(4-Benzofuran-2-yl-5-pyridin-4-yl-1H-imidazol-2-...)Copy SMILESCopy InChI

Affinity DataIC50:  1.00E+5nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI