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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
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Affinity Data
Ki: 0.170nM
Assay Description:
Inhibition of human recombinant FLT3 by radiometric assay
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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Article
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
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Affinity Data
Ki: 2nM
Assay Description:
Displacement of [33P]ATP from human recombinant FLT3 domain after 20 mins by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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Article
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Target
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
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Affinity Data
Ki: 40nM
Assay Description:
Inhibition of AXL
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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In Depth
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Article
PubMed
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Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
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Affinity Data
Ki: 85nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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Article
PubMed
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Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
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Affinity Data
Ki: 130nM
Assay Description:
Inhibition of cMET
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Article
PubMed
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Target
Angiopoietin-1 receptor
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
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Affinity Data
Ki: 200nM
Assay Description:
Inhibition of Tie2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Article
PubMed
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Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
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Affinity Data
Ki: 200nM
Assay Description:
Inhibition of PDGFR-beta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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GoogleScholar
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Article
PubMed
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Target
Lysine--tRNA ligase
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
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Affinity Data
Ki: 220nM
Assay Description:
Inhibition of SYK
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
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Affinity Data
Ki: 280nM
Assay Description:
Inhibition of Jak3
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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In Depth
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Article
PubMed
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
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Affinity Data
Ki: 400nM
Assay Description:
Inhibition of ABL
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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CHEMBL
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Article
PubMed
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Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
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Affinity Data
Ki: 400nM
Assay Description:
Inhibition of LCK
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Tyrosine-protein kinase Lyn
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
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Affinity Data
Ki: 400nM
Assay Description:
Inhibition of Lyn
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Article
PubMed
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Target
Fibroblast growth factor receptor 3
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
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Affinity Data
Ki: 400nM
Assay Description:
Inhibition of FGFR3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
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Article
PubMed
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Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
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Affinity Data
Ki: 770nM
Assay Description:
Inhibition of Src
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
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Affinity Data
IC50: 4nM
Assay Description:
Inhibition of c-KIT-mediated ERK 1/2 phosphorylation in human TF1 cells at 4 to 12 nM after 1 hr by immunoblot analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50355491
(CHEMBL1835870)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4nM
Assay Description:
Inhibition of SCF-induced phosphorylation of c-KIT in human TF1 cells after 1 hr by immunoblot analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI