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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical
Ligand
BDBM6877
(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3m ...)
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Affinity Data
IC50: 3.70nM
pH: 8.0 T: 2°C
Assay Description:
The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 10 uM ATP/[gamma-33P]ATP in a streptavidin coated ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Interferon-induced, double-stranded RNA-activated protein kinase
(Homo sapiens (Human))
Weill Cornell Medical College
Curated by
ChEMBL
Ligand
BDBM6877
(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3m ...)
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Affinity Data
IC50: 8.00E+3nM
Assay Description:
Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI