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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Methylated-DNA--protein-cysteine methyltransferase
(Homo sapiens (Human))
Newcastle University
Curated by
ChEMBL
Ligand
BDBM5484
(6-(cyclopent-1-en-1-ylmethoxy)-9H-purin-2-amine | ...)
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Affinity Data
IC50: 200nM
Assay Description:
concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Methylated-DNA--protein-cysteine methyltransferase
(Homo sapiens (Human))
Newcastle University
Curated by
ChEMBL
Ligand
BDBM5484
(6-(cyclopent-1-en-1-ylmethoxy)-9H-purin-2-amine | ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 390nM
Assay Description:
Inhibition of AGT activity to 50% of control rate in HT-29 cell extract
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1
(Homo sapiens (Human))
University Of Zurich
Curated by
ChEMBL
Ligand
BDBM5484
(6-(cyclopent-1-en-1-ylmethoxy)-9H-purin-2-amine | ...)
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Affinity Data
IC50: 1.90E+4nM
Assay Description:
Inhibition of CDK1/Cyclin B
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B
(Marthasterias glacialis (starfish))
University Of Newcastle
Ligand
BDBM5484
(6-(cyclopent-1-en-1-ylmethoxy)-9H-purin-2-amine | ...)
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Affinity Data
IC50: 1.90E+4nM
Assay Description:
The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2
(Homo sapiens (Human))
University Of Newcastle
Ligand
BDBM5484
(6-(cyclopent-1-en-1-ylmethoxy)-9H-purin-2-amine | ...)
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Copy InChI
Affinity Data
IC50: 3.10E+4nM
Assay Description:
The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI