Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5484(6-(cyclopent-1-en-1-ylmethoxy)-9H-purin-2-amine | ...)
Affinity DataIC50:  200nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5484(6-(cyclopent-1-en-1-ylmethoxy)-9H-purin-2-amine | ...)
Affinity DataIC50:  390nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM5484(6-(cyclopent-1-en-1-ylmethoxy)-9H-purin-2-amine | ...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University Of Newcastle

LigandPNGBDBM5484(6-(cyclopent-1-en-1-ylmethoxy)-9H-purin-2-amine | ...)
Affinity DataIC50:  1.90E+4nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of Newcastle

LigandPNGBDBM5484(6-(cyclopent-1-en-1-ylmethoxy)-9H-purin-2-amine | ...)
Affinity DataIC50:  3.10E+4nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed