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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
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Target
Adenosine receptor A1
(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by
ChEMBL
Ligand
BDBM49037
(4-amino-2,6-diphenyl-5-pyrimidinecarbonitrile | 4-...)
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Affinity Data
Ki: 10.8nM
Assay Description:
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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Article
PubMed
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by
ChEMBL
Ligand
BDBM49037
(4-amino-2,6-diphenyl-5-pyrimidinecarbonitrile | 4-...)
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Affinity Data
Ki: 19nM
Assay Description:
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
D(1A) dopamine receptor
(Homo sapiens (Human))
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by
PubChem BioAssay
Ligand
BDBM49037
(4-amino-2,6-diphenyl-5-pyrimidinecarbonitrile | 4-...)
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Affinity Data
EC50: 0.00117nM
Assay Description:
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
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Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
Broad Institute
Curated by
PubChem BioAssay
Ligand
BDBM49037
(4-amino-2,6-diphenyl-5-pyrimidinecarbonitrile | 4-...)
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Affinity Data
EC50: >3.00E+5nM
Assay Description:
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI