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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Merck And
Curated by
ChEMBL
Ligand
BDBM50448786
(CHEMBL3128194)
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Affinity Data
IC50: 1.83E+4nM
Assay Description:
Inhibition of CYP2D6 in human liver microsomes assessed as dextromethorphan O-demethylation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Merck And
Curated by
ChEMBL
Ligand
BDBM50448786
(CHEMBL3128194)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of CYP2C9 in human liver microsomes assessed as diclofenac alpha'-hydroxylation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Beta-3 adrenergic receptor
(Canis familiaris)
Merck And
Curated by
ChEMBL
Ligand
BDBM50448786
(CHEMBL3128194)
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Affinity Data
EC50: 0.190nM
Assay Description:
Agonist activity at dog beta-3 adrenergic receptor expressed in CHO cells assessed as increase in intracellular cAMP accumulation after 30 mins by ti...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Beta-3 adrenergic receptor
(Macaca mulatta)
Merck And
Curated by
ChEMBL
Ligand
BDBM50448786
(CHEMBL3128194)
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Affinity Data
EC50: 0.0600nM
Assay Description:
Agonist activity at rhesus monkey beta-3 adrenergic receptor expressed in CHO cells assessed as increase in intracellular cAMP accumulation after 30 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI