Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL

LigandBDBM50015769(8-Fluoro-[1,2,4]triazolo[4,3-a]quinoxalin-4-ylamin...)Copy SMILESCopy InChI

Affinity DataIC50:  1.00E+3nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetAdenosine receptor A1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL

LigandBDBM50015769(8-Fluoro-[1,2,4]triazolo[4,3-a]quinoxalin-4-ylamin...)Copy SMILESCopy InChI

Affinity DataIC50:  2.90E+3nMAssay Description:Binding affinity towards the adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]CHA as radioligand.More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B/Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C/Phosphodiesterase(Rattus norvegicus)
Pfizer

Curated by ChEMBL

LigandBDBM50015769(8-Fluoro-[1,2,4]triazolo[4,3-a]quinoxalin-4-ylamin...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Evaluated for Ca++ dependent phosphodiesterase activity.More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI