Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetEphrin type-B receptor 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50195879(3-(4-amino-3-(3-chloro-4-fluorophenyl)thieno[3,2-c...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human EphB4 by scintillation proximity methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50195879(3-(4-amino-3-(3-chloro-4-fluorophenyl)thieno[3,2-c...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human recombinant GST-6XHis-VEGFR2 by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50195879(3-(4-amino-3-(3-chloro-4-fluorophenyl)thieno[3,2-c...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Akt3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50195879(3-(4-amino-3-(3-chloro-4-fluorophenyl)thieno[3,2-c...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAPKAPK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50195879(3-(4-amino-3-(3-chloro-4-fluorophenyl)thieno[3,2-c...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50195879(3-(4-amino-3-(3-chloro-4-fluorophenyl)thieno[3,2-c...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GSK3bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50195879(3-(4-amino-3-(3-chloro-4-fluorophenyl)thieno[3,2-c...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IKK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50195879(3-(4-amino-3-(3-chloro-4-fluorophenyl)thieno[3,2-c...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50195879(3-(4-amino-3-(3-chloro-4-fluorophenyl)thieno[3,2-c...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50195879(3-(4-amino-3-(3-chloro-4-fluorophenyl)thieno[3,2-c...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant GST-Tie2 by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed