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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Interleukin-1 receptor-associated kinase 4
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM50068467
(CHEMBL3403445 | US9598440, 11)
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Affinity Data
IC50: 409nM
Assay Description:
Procedure: A 20 μl reaction mixture contains 10 mM TriHCl, pH 7.2, 0.5 nM GST tagged IRAK4 (SignalChem), 100 nM fluorescent peptide substrate (R...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Interleukin-1 receptor-associated kinase 4
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM50068467
(CHEMBL3403445 | US9598440, 11)
Copy SMILES
Copy InChI
Affinity Data
IC50: 410nM
Assay Description:
Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI