Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Astex

LigandBDBM15787(3-N-{[5-(1H-indol-6-yl)-2-(pyridin-2-ylmethoxy)phe...)Copy SMILESCopy InChI

Affinity DataIC50:  4.20E+3nMpH: 5.0 T: 2°CAssay Description:Activity of BACE-1 was measured by monitoring the cleavage of its peptide substrate on a Fluoroskan Ascent plate reader with excitation and emission ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoDrugBankMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedMMDB
PDB3D Structure (crystal)
Copy BDB DOI