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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
NAD-dependent protein deacetylase sirtuin-2
(Homo sapiens (Human))
University Of East Anglia
Curated by
ChEMBL
Ligand
BDBM50343897
(8-phenyl-Adenosine Mono Phosphate | CHEMBL1775011)
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Affinity Data
IC50: 2.90E+4nM
Assay Description:
Inhibition of human recombinant N-terminally His6-tagged SIRT2 after 4 hrs by homogeneous fluorescent deacetylase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
NAD-dependent protein deacetylase sirtuin-1
(Homo sapiens (Human))
University Of East Anglia
Curated by
ChEMBL
Ligand
BDBM50343897
(8-phenyl-Adenosine Mono Phosphate | CHEMBL1775011)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.10E+4nM
Assay Description:
Inhibition of human recombinant GST-tagged SIRT1 after 4 hrs by homogeneous fluorescent deacetylase assay
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI